Crohn’s disease is a chronic inflammatory condition that can affect the entire body, and one often overlooked symptom is night sweats. These episodes of heavy sweating during sleep aren’t just discomforting; they can signal underlying issues that need attention. Understanding the causes and how to manage them is key to improving quality of life for those living with Crohn’s.
Why Night Sweats Happen with Crohn’s
The primary driver of night sweats in Crohn’s is inflammation. When the disease is active, the immune system releases chemicals called cytokines (like IL-6 and TNF-α) that essentially “reset” the body’s thermostat in the brain. This leads to a low-grade fever that peaks at night, resulting in drenching sweats.
However, inflammation isn’t the only culprit. Infections, particularly in those taking immunosuppressant medications, can also cause night sweats. Biologic drugs, while effective, increase the risk of infections like C. diff or tuberculosis, which often present with this symptom. In rare cases, night sweats can even be a sign of cancer, specifically lymphoma, in individuals exposed to certain Crohn’s medications like azathioprine or anti-TNF drugs.
Finally, hormonal changes, such as those experienced during perimenopause or menopause, can exacerbate night sweats in women with Crohn’s.
How to Manage Night Sweats
If your doctor has ruled out other causes, here’s what you can do to manage night sweats related to Crohn’s:
1. Limit Evening Triggers: Avoid alcohol, nicotine, spicy foods, and heavy meals close to bedtime. These can worsen inflammation and trigger sweating.
2. Exercise Strategically: Regular physical activity can reduce Crohn’s activity, but avoid intense workouts late at night. Aim for at least 150 minutes of moderate exercise per week.
3. Optimize Your Sleep Space: Keep your bedroom cool, use breathable bedding, and consider a fan to regulate temperature.
4. Medication Review: Certain Crohn’s medications (adalimumab, infliximab, leflunomide, mycophenolate mofetil, tacrolimus) can cause or worsen night sweats. Discuss timing or alternatives with your doctor.
5. Symptom Tracking: Keep a log of your night sweats, including temperature, stool frequency, pain levels, and timing. This information can help your doctor adjust your treatment plan.
6. Consider Acetaminophen: If your doctor approves, taking acetaminophen before bed can help manage fevers and reduce sweating.
When to See Your Doctor
Night sweats with Crohn’s aren’t always a cause for alarm, but they warrant attention if they are:
- New or worsening
- Accompanied by fever over 100.4°F
- Paired with unexplained weight loss or pain
The Bottom Line
Night sweats are a common symptom of Crohn’s disease, often linked to inflammation, infection, or medication side effects. By understanding the causes and taking proactive steps to manage them, you can improve your sleep and overall well-being. If your symptoms are severe or persistent, consult your doctor for further evaluation and treatment
